I only have two personal anecdotes here. I went hunting with a friend on some ranch/farm he had access on, very much in prairie country Eastern AB. He was after a mule deer buck, and 'technically' I had a legal tag for a WT buck, though I didn't expect to see one. We were walking either side of a little gully, came around a bend and spotted some mule does bedded down. Johnny was getting ready to bust his buck out of cover!
When the does finally got up and started moving away from us, 'technically' the biggest frakkin' WHITETAIL buck I've personally had a chance to shoot got up from his bed maybe 45 yards further up, looked me right in the face, and took off with his girlfriends in tow, great big whitetail ass flagging all the way. I had a round chambered and safety on, but gobsmacked incredulity cost me the buck. It can happen even in wide open country.
I was hunting grouse with my great friend and my dog, both of us had double shotguns, loaded of course.
Mine was a Red Label, tang safety of course on. I stepped over a log or something, got my feet tangled up, and went ass over ego on the ground. What I noticed in that weird slow-mo second was that I thought consciously about keeping those barrels pointed at the sky, finger alongside and thumb reinforcing the safety. IDK how I managed that and without a scratch on my friend, my dog, my gun or my personage.
I do trust modern safeties on guns that are in good condition, for some reason the half-#### on a lever gives me the creeps though.