7.62x51 and 308 are the same thing.
223 and 5.56 are the same thing.
Being a real human with a brain:
Totally interchangeable as NATO isn't that much hotter. Go nutz (and you are nutz if you plan on shooting factory ammo $$$)
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..there's several Milsup rifles chambered for 7.62x51mm NATO that cannot take the higher-pressure, heavier-grain .308 commercial ammo. 


























