I used some when I first started with my No.4 and they were certainly accurate enough but I never used 150gr ammo for hunting, preferring the 180gr. until I started reloading. I have used Sierra 180 and 125 gr. Speer 180 gr. and Hornady 174 gr. for my reloads. I've taken deer with both sizes of Sierra and with what became my favourite, the Hornady. If I had to buy commercial loads I wouldn't be afraid to use Federal stuff, based on my limited experience of them, but would choose 180 over 150, if available.