i guided for three seasons for caribou in the fall so i may have a good idea what will work .... i used in no preference order Martiini Skinner , havalon piranta, outdoor edge kodi pack, Camillus Skinner (the one made in usa) buck 109, 119, 102, 102, 110, folding buck with sv30 blade, mora of all sort including the 2000 (very good but no hand guard ...) so in fact as you re able to keep a knife sharp all will work just a matter of preferences.
and Doug mention a point about hair ill listen him ... skinning a caribou is hard on the edge too ....
a mora is really a good start. i always had and still have one with orange color (you wont loose it dont ask lol) + a gerber folding/collaspible (sp) saw with wood and bones blades can be helpful for the skull. the Wyoming are great but avoid those with leather sheet (more heavy and their steel dont like moisture trapped in)
but for a matter of use two moras and a little ceramic sharpening stuff will work. for everything from moose to any other game (maybe not the bison but why not ...)
now a buck vantage knife with rubber handle and sv30 will be another good choice.
the ultimate for lazy will be Havalon but they are really sharp ....
did i forget mention Mora knife lol ....
have a good selection time ..