I had a gun with a 1:48 twist and found that it could do both jobs very well. It took some trial and error but it could produce acceptable accuracy for hunting conditions. You will have to try different ball and patch sizes (you have to do this with any gun...) and of course, charges of powder. I found mine could shoot Lee REAL bullets and sabots and in actual fact, produced my best 100 yard group with the sabots. Not sure why they worked so well, maybe the plastic cup base as they were tight going down the bore. I think if you are shooting with iron sights 100 yards should be your longest shot but you can use your own best judgment.
Cheers. Steve