Anything is possible but it would not be as simple as drilling a single hole. Glock firing pins are not round at the tip, they are oblong and so is the hole for them to protrude though in the breech face. They are also pretty deep to access from either end of the slide. I am sure a machine shop could get it done, but what would the cost be to have them do a specialized one off job like this.
Then you would have to consider the responsability you would have to take, in that the slide has a warning roll marked right into the side "WARNING-DANGER practice pistol do not load or fire live ammunition". If I was at the shooting range and someone was beside me shooting something with a warning like that I would personally worry for their saftey and mine and move away. If I owned or worked at the range, I would kindly tell them Im sorry but I cant let you shoot that here.
Even if you could get the firing pin oblong hole done, there is no information that I can see that the slide material is made of the same as a standard slide. Glock may possibly use a weaker material as the slide was never made to fire live ammunition.
Buying the practice with the intention of converting it to a live fire pistol IMO would only be a good for someone like me that already owns Glock 17's or 17 slides. Or doesnt mind spending quite a bit more money to buy a complete slide, or piece one together using either OEM Glock or aftermarket options.
As has already been pointed out, there is an inherent danger associated with converting a known and easily identifiable inert practice pistol into one that fires live ammunition. Aside from the practical reality that converting one is likely more expensive than just buying a G17 gen 3, it's also a really bad idea?




















































