Holy Crap! Airskinning looks like the best idea since sliced toilet paper; I am trying that ASAP!
As far as the original question goes: less analyzing and more shooting...with any of those guns...will do you a world of good. You can't "math" a coyote to death, you gotta shoot him.
And it's a hoot to hear a newer shooter oohing and aahing over the .25-06; it's been around as a factory cartridge for 45 or 50 years, much longer as a wildcat. It was the top choice in a high-velocity round back then, and still a great choice today...plus, it's apparently become new and exotic again!
But it'll be a shame when you buy one and expect your older shooting compadres to faint with the shock of seeing it...and they just say "That's nice..."