Light for caliber monolithic bullets perform far better than most folks who never try them could imagine.
Take for example using a 100gr. original Barnes X out of a .270Win. Out of a 22" barrel the load used ran just under 3500fps.
The shooter is my wife, she harvested 2 moose, numerous deer, 1 black bear and 1 antelope with this combination.
It's hard to understand for those used to conventional bullets that with near perfect weight retention that the monolithic's can and do perform like Nosler Partition's which weigh 20-25% more.
To explain this, I will say I was un convinced when I had the conundrum of my wife getting scope kissed, and getting an outrageous flinch, that no matter what I tried she couldn't overcome.
I tried loading some varmint bullets out of her .270, and her form got far better, but that's fine for practice, what about big game?
The Internet was in its infancy back then so it was time to search printed catologues and the like.
I ordered up some Barnes X 100gr., and lo and behold a just under max load of IMR 4350, yielded exceptional accuracy out of that .270.
I still had my misgivings especially on larger critters than deer, though.
I've known that the 130gr Partition was a solid performer in the .270 for larger game, so I set up a head to head challenge.
I loaded up some Partition 130's for a muzzle velocity of around 3000fps, and I also loaded some of those 100gr. X's to around 3500fps. This gave 100yard impact energies of about 2250ftlb, or there abouts + or -.
I then made up 2 identical expansion boxes made of water logged catologues. They were assembled as such. 1, 3/4" catologue, then 1 piece of 3/8"OSB, followed by more soaked catologues to fill out the 24" of box.
The catologues had been soaked in my bath tub over night , and rotated at least 3 times over the period, all the catologues were very thoroughly soaked, and it took many trips with them in garbage bags to get them all out to the truck.
I assembled the expansion boxes at the 100 yard target line at the range, and then fired a shot from each loading into the center of each box (after confirming zero on paper for each load)
My notes indicate the following.
100gr. X: 14" penetration, 99% weight retention(99gr), frontal diameter 0.8"-1".
130gr. Part.: 13" penetration, 67% retention(87gr), frontal diameter 0.5-0.6"
Holy cow, I could drop, some 23% in bullet weight, and yield near identical results!
My wife went on to shoot her first moose that fall, a nice meat animal at about 65yds, it simply lunged forward once hit, nosed in, and died from the double lung shot, which exited.
I see no reason why 110gr TSX's in 30 cal. would be a whole lot different than my experience with original X's. if someone made something like a 140gr Partition in .30 cal. I'd expect they'd perform similarly.
What sort of accuracy you'll get is up to the rifle to decide, mind you.
As for .300 Win Mag, loading, I think you'll find some pretty wonky pressures and the like, that's a pretty light pill, for a pretty large combustion chamber... But you won't know till you try.
Report your results, we seldom here how stuff turns out for guys around here.