I've had great results with Interlocks. Not only are they some of the most accurate bullets I've worked with but deadly as well.
A friend of mine here in south east BC, who is a very experienced and successful Elk hunter (but not a reloader) has a Tikka in 300 wsm that he's had trouble finding factory ammo that shoots well in his rifle.
I worked up a super accurate load for him using a 180 grain Interlock SP, and every year since, he's taken a 6 point bull at ranges between 200 - 300 yards with those Interlocks, usually the Elk will take less than 20 steps before dropping dead.
I've tried giving him Accubonds and Interbonds to shoot, but he keeps coming back to those Interlocks, as nothing else works as good in his gun.
As others have mentioned here and elsewhere, it's important to keep jacketed bullets below 2900 fps.
For my rifles I do prefer Accubonds, Interbonds, and TTSX's, because I'm hunting in grizzley country here,
but I wouldn't hesitate to hunt with Interlocks.
I usually work up new loads with inexpensive bullets like Interlocks, then switch to a bonded or copper bullet, then do a little tweaking.