I just read this thread as well and have experienced the same as dogleg, Dave and Bruce............however low ES and SD do not an accurate load make....I had a Rem 700 HB 22-250 that I shot 3 consecutive 3/8" groups with a 52 gn load, the load chrono'd with 138 fps ES. I have also chronographed a load last summer that had an ES of 5, 7 and 8 for 3 loads of 4 rounds each, but wouldn't shoot into 2" at 100 mtrs. ES nearly always comes down as pressure goes up, I think we all agree on that. ES also seems to go down as case fill comes up, I almost always try to use a powder which produces a compressed charge. Finally as dogleg said neck tension consistency will affect your ES as well. Until you get your ES down into the 20-30 fps with pressure, fill and neck tensions, you can forget about BR primers and weighing cases and all the other bench prep advice that has been given. Deburring flash holes and uniforming primer pockets, ain't gonna do squat for your ES, sorry.
In nearly all my rifles and calibers that I have loaded for and played with, it has been my experience that moderately heavy-for-caliber bullets with as slow a powder as one can use in that case to produce the highest velocities, when compressed lightly, will NEARLY always give the lowest ES/SD and be one of the most accurate loads for that cartridge/caliber. JMHE and YMMV