A consistent powder charge is important for accuracy.
That said, it's a combination of parameters that begets a good load, these are:
Low variance of case volume
Concentricity of the loaded round
Consistent neck tension
Primers seated to a consistent depth
Consistent powder charges +/0 0.02 grains
Do all that and you load still might not perform, the key is finding OCW (OCW will be one that has all of the deterrent chemicals consumed at peak pressure 'optimum burn') and the charge weight produce a velocity that is on a barrel node.
Sketchy velocity readings can be resolved using a LabRadar or Magneto-Speed, barrel nodes and optimum burn can be found using QuickLoad.