I have used Hornady bullets with reasonable success [with one exception], but stay away from the Interlock in any magnum.
The Interbond is a great bullet, and the GMX, being monometal, is good as long as velocity is up there.
I had a 270, 140 grain SPBT Interlock from a 270 Winchester blow up completely on a whitetail deer's ribs [c. 80 yards]
That bullet started at just over 3000 with the load I was using, and no part of the bullet reached the vitals.
Fortunately for me [and the deer] he only ran a few yards and stopped, seemed a bit dazed, and I was able to give him
a second shot, at which he dropped immediately. He had a large surface wound from the first shot, but the second was
a passthrough. Maybe just a faulty bullet, but it put up caution flags for sure. My 270 now gets the 140 Accubond.
For my 257 Weatherby, the only bullets I load and use are: 120 Partition, 120 A-Frame, 100 TTSX.
In my 6.5x55AI, the 142 LRAB seems to work well, but 2 animals is hardly a big enough number to assess properly.
My 8mm Rem Mag gets the 200 or 220 A-Frame, with the 196 Oryx a tentative candidate, we'll see. Dave.