IMR3031, 4227,4198 and AA5744 will likely be the most useful powders, they cover pretty much all the bullet weights. It's possible that 4064 may work with some very hard cast bullets, I'd have to research that, there is a group of shooters that run cast at 2500fps plus, up to 3000 IIRC, pretty specialized discipline, They used to frequent Castpics, not sure it even has a forum there anymore, haven't looked seriously at that site in ages, some may post on CBA or Cast Boolits, fella named Larry ????? used to post on Cast Boolits, say 15 yrs ago, then he and some others started Castpics. They shot mostly all high speed stuff, 30BR was one I remember, some were heavily into, along with 308.