With mono's, think lighter and faster. A 140 gr TTSX will perform like A 160 gr partition because the 140 gr mono will retain at least 90%+ of its original weight and penetrate like nothing else! Since you're shooting a 7mm Rem Mag, I'd lean towards a 145/150 gr mono bullet, myself. You need at least 2000 fps impact velocity to ensure proper expansion (min 1600 fps for the LRX according to Barnes). So if you launch a heavy mono at slow muzzle velocity, you will limit your shooting distance and risk a poor performing bullet if you are shooting at the max distance of the velocity envelope. All those 'barnes don't open' nay-sayers are pretty much shooting or have seen shots past the velocity envelope. I've never had a bad shot or 'kill' with a Barnes. All the animals have been done on first shot. (Pretty much all my hunting loads are TTSX/LRX bullets... except my 270 for which I use Nosler AB's. Just happened to be an accurate load so stuck with it!)