Hunting? Targets? What range?
I use 180gr Speer Spitzer Soft Points, and 75.5gr Reloader 25, which is the starting load listed in Speers #14. I get under 1 inch at 100, and smash clays at 200, I'd try for longer, but that's as far as my range goes.
Do you have a manual? I'd recommend at least a couple, they are packed with a lot of great info. I read mine fairly regularly, just for kicks.