Screw the 22!
Let me tell you some of my experience teaching the (as she calls herself) "Better Half" to shoot...
We started out with her purchasing the Sig Mosquito with the full package (Scope base, holster, crappy little dot sight). She quickly moved up to a 40mm tasco dot because the little one included had such a limiting field of view.
After a few visits to the range she became quite good at nailing the center of the target, however she quickly became fustrated with the reliability of the Sig 22 (but she did learn to clear her own Jams!).
Another visit to the P&D for us and she bought herself a 40S&W P226 and some 165 grain bullets. I handload them to around 800fps for a nice light snack
She had no problem polishing of the 50 test rounds and wanted more.
Now, the collection has grown yet again - Went to get myself a pound of powder (P&D - you own my soul I swear!) and she fell in love with a nice CZ75B in 9mm.... Something I tried to talk her into in the first place!
Summary of this long story...
Get her a nice 9mm! Screw the 22 pistol. With some basic handloads you could make it a comfortable little shooter, the brass is cheap (I love free range brass!) and bullets aren't that bad. If you don't handload - its one of the cheapest calibers to shoot.
Beginner shooters get fustrated pretty easy by "issues" while learning. Having a fussy 22LR jamming can really slow down the
FUN of the experience!
FYI - The CZ only cost a hundred more than the Sig 22 when all was said and done - money well spent!
Here is a picture of her new baby for you to enjoy - she now has it as a windows background!