I realize this might be unrealistic for most, but my S&W M18 is just about everything I could ask for in a .22 revolver. Fits me well, good sights, good trigger in both hammer and trigger cocking. It doesn't like most cheap ammo, but it loads and ejects the Federal 525 bulk pack stuff just fine, and that works out just fine for me. It looks and feels virtually identical to my M15 .38 Special, so it is a great practice piece.
But yeah, it's 12(6) prohibited due to the 4" barrel length. I'm not sure what their current options are for a K-frame .22.