Not really, no.
FL resizing MAY be needed, but you never know until you actually try. I have rifles that I can neck size only and use my reloads in more than one rifle of the same caliber, without problems.
Having to work up loads for each rifle is another often repeated pile of complete BS. If a factory can produce .308 ammo that works in tens of thousands of 308 rifles out there, then so can you. Having to work up loads for each rifle is only for those who are pushing their loads right to the maximum, either in terms of pressure or accuracy or whatever. If your ammo is reloaded to accepted factory specs it WILL work in multiple rifles, assuming there is nothing wrong with the rifle. That's the whole point of actually having standardized specs for each cartridge - neither the factory producers, nor the handloaders have to start from scratch with each rifle. I reload for five 308's myself, not all of which I own, and I have one recipe for all these rifles and the ammunition I reload works very well in all five rifles.