Have you tried in 44 mag? And what primer did you end up using after?
Yes, I tried IMR4227 with both regular and magnum primers in 44magnum. 22.0 to 24.0grn in 0.2grn increment. Gun is a desert eagle, 6'' barrel. With a regular primer (CCI 300) it won't even cycle the gun even if I use the maximum load, and there's some unburnt powder. With a magnum primer (CCI 350), at maximum load, the gun cycles 100% of the time and the powder burns clean. It feels slightly less powerfull than H110, and without the fireball. Using the same bullets as you, campro 240grn.
I've made quite some experiment with that deagle, trying different powders and primers. Some powders need magnum primers (IMR4227 and H110 among others) and some others need regular primers (titegroup, Win231). Do not use a very fast powder such as titegroup with a magnum primer, it will create a pressure spike and propel the bullet without stabilizing it (I have no clue if the pressure spike is enough to be dangerous, and although I guess not, I won't test it again). And do not use a slow powder such as H110 with a regular primer, it will leave a quantity unburnt (how much will depend on many other factors, including bullet weight and crimping), which can ignite on subsequent shots or just make your gun dirty AF.
IMR4227 is slightly faster than H110, so it will go bang with a regular primer, but the result will generally s*ck.
To recap, in 44magnum:
H110/Win296, IMR4227: Use magnum primers.
titegroup, Win231, HS6, 700X, 800X: Use regular primers.
Which gun are you reloading for? Realoding for revolver or lever action rifle you can do pretty much anything, for a semi-auto there's a lot of stuff that will go bang but won't cycle the action.