The rule of thumb is that you don't need to turn the necks if your runout is within .004", and then just turn to trim off the high spots. As Maynard said, the advantage of turning with a factory chamber is of questionable value.
Variations in bullet pull weight are a related but separate issue, and to uniform your bullet pull weight there are a number of things you can do. Use the Sinclair neck expander to slightly oversize the neck, then use a bushing die to size it. Bushings are available in a broad range of sizes. To determine the correct one, add the neck thickness X 2 to the bullet diameter to determine the correct bushing size. Anneal the case necks after each firing. Work up you loads with the bullet seated into the lands. This eliminates the issues related to variations in bullet pull weight. Some folks claim that better accuracy is observed when you seat off the lands, that is only true when you want to achieve the highest possible velocity as in the case with hunting loads. Once the maximum load has been determined with the bullet seated into the lands, you can work backwards to find the best accuracy.
If you are loading hunting bullets with cannelures, crimping the bullets in place also uniforms the bullet pull weight, and allows the round to be chambered from the magazine. Some folks don't have an issue crimping bullets without cannelures, but I prefer to choose those bullets for target shooting applications and seat them into the lands.