22/250 or .223 a distant second if you want to do it the easy way. The 22/250 has an edge on the coyotes and the .223 for throwing a pile of rounds down range due to less heat.
x2. The .223 with undoubtedly do it, but once you start hammering coyotes past 200 yards, you will see how the .22-250 really anchors them. I used to shoot 60 grain Hornady sp's out of a .22-250 and they really put the dogs down.




















































