It's not much of an issue with Does, or spike bucks, but the larger bucks have glands in their necks that enlarge because of the hormonal changes they go through during the rut.
These bucks commonly slurp up excretions and urine from the Does in Estrus during the rut, this causes all sorts of changes to their overall physical/mental status.
When you skin these bucks, the glands are easy to find in the necks, which are usually quite swollen from the fluid filled glands and the issues they create with the neck muscles.
One of the best things you can do is to remove these glands as quickly as possible, before they drain into the body of Deer, altering the flavor of the meat.
There is one large gland, appx 20cm long, and can be up to 7-8cm diameter at the center on each side.
Most folks don't even know they're there. Some folks say they aren't. Usually because they don't look for them or view the neck areas until they get the animal home, then it's too late.
If you get the Buck late in the season, I don't know if removal of the glands makes much difference.
I was shown the glands when I first started hunting, and depending on the age of the buck, they can be huge or the size of your pinky finger.
The best thing you can do for the flavor of your animal is to cool the meat down, by whatever means as quickly as possible, after bleeding it properly.