That's the way it goes.
And BTW, this is OK and expected. In most cases, this is an accurate-enough metering of powder charges.
I use a Redding BR-30 (a reasonable quality powder measure). If I throw 50 charges of Varget or Reloder-15 (stick powders, but shorter grained and a bit better metering than 4350), most of the charges will be within a 0.4 grain interval, i.e. my target weight +/-0.2 grains. **BUT**, out of the 50 charges that have been carefully thrown, the spread from the lightest to the heaviest charge is usually 0.8 grains or even as much as 1.0 grains.
I use these thrown charges in my .308 match ammo, without reservation out to 600m at any level of competition; it easily and consistently shoots honest sub-MOA. Some particular load combinations (e.g. my load with Varget and #2155 Sierra 155) are consistent enough to shoot well at 1000 yards with thrown powder charges (though I admit that I do weight and trickle some of my 1000y ammo). The funny thing is, the biggest match I ever won in my life was fired at 1000y, and I used borrowed ammo made for a friend's rifle - Sierra #2155s seated to magazine length and thrown powder charges!