Opinions - appropriate bullet weight for .30-06 for deer hunting

Because the Hornady Interlock is designed with a certain velocity window in mind, and if the bullet strikes an animal above that window, it may come apart.

Beside that, bullet makers typically build heavy-for-caliber bullets a little tougher than the lighter bullets. The 110gr bullet may be designed with varmints in mind, rather than big game, as where the 100gr .243 bullet is designed specifically for shooting deer.
 
I begin to wonder, now that we are here;and I will just throw this out, ready to take the flaming; why can we accept that a 90gn .243 Hornady standard bullet will kill a deer at 200yds, but a 110gn .308 Hornady standard bullet will not?

Just putting this out. I DO NOT HUNT BIG GAME WITH A 110gn .308 BULLET. But I do hunt big game with a 100gn .243Win.

If its a bullet like the Barnes type solid that i misunderstood you were referring to rookie, it will work fine at 200 yards. It's only the varmint construction designed to prevent ricochets, that may make a grevious though superficial wound anywhere into the body. I like to have a place to set up a controlled test with a Deer Hide/Rib cage with a heart suspended inside a ballistic gel mix directly behind, to see what a varmint 110 at velocities from 25 yds out to 200yds. Would be interesting to see the results . I saw someone use this controlled test with a Beef heart to compare various bullet weights in a 10mm pistiol and it looked like a sensible laymans test setup.:wave:
 
im in agreement with 1899 post heavier grain , less defragmentation. i run a 175 gr on my 7mm mag on blacktails works well. less damage to meat comparitvely to my buddy who uses 150 gr. same cal.
 
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