I currently own 3 rifles, one is DD MK18 with quad rail, the other I put a Spikes Bar2 on it that is also a quad rail. Now I just got a PSA upper pica-tiny top rail but with Keymod on the sides and bottom. I really like the feel of the keymod rail, even without rail covers like I need for the quad rail its still more comfortable in the hand.
The problem is its harder to find accessories that use Keymod, I had a hard time finding a vertical foregrip I liked, I finally found one and ordered it. And when it got here it would not fit my rail, the grove that the rail is supposed to sit between was too narrow. I had to machine off 0.0100 for it to fit.
So I think they are really nice feel in the hand and really light, but if you want accessories its harder to find them in keymod. And or you need mounts that go from Keymod to picatiny rail to mount your accessories anyways...
Another thing is I find they dont have the same range of adjustment in terms of where you can mount your keymod accessories, for my foregrip it seems it can only be mounted a little father forward or back of where Id really like it. On a quad rail it seems to have a finer range of placement as each groove is closer together compared to keymod they are father apart