I think if I did a lot of big game hunting, all over the world, and could have only 1 gun, it would be a 375 H&H, built on an FN action, with battue sights. Yes, there are more modern calibers that surpass it in terms of ballistics, but with 105 years of extremely solid and reliable performance, I don't think anything can match it. You can use it from deer-sized to elephant-sized game, at ranges from point-blank to 400 yards. And you know the ammo wil always be available, whereas the same can't be said for some other 375's.