You have to ask yourself an important question:
Do I plan to shoot only light competition PPC/IPSC loads with this gun? Jerry Miculek doesn't exactly shoot full house .45acp...
If you "chamfer" the chambers, you have changed the dimentions of each one, your brass will swell at the base just a little bit more, so you have to remove more metal from the extractor, or you may lose consistant ejection of non-mooned cases (.45 AR), small rims (.45Colt).
As with any mechanical relationship, each action causes/creates cascading changes.
Maximum charges may no longer function reliably in your gun (extreme case perhaps, but possible).
Rounding (barely cutting) the sharp corner edges of the extractor & polishing the chambers is the most I would have done.
I've seen "chamfering" jobs that look like someone used a 3 cornered file...
It is VERY important to realize that you can go too far & do serious damage to your gun.
The relationship of the extractor is very finely fitted, and I've seen some EXTREMELY VALUABLE guns which were funged by people who did "easy" stuff wrong.
Remember, you have 6 tries to get it wrong....