Oh, you'll certainly have to dress the front sight down a hair. I don't know for sure but I THINK that they copy the original sight blades that are used in the .45Colt guns which have lighter barrels due to the thinner walls from the bigger bore. Everything else gets the same sight blade. So when I got my .357 model Pietta SAA's they shot low by about a yard or so at 20 feet....
But really other than the personal concern or screwing up this is a good thing. I'd rather buy a gun like this which I need to take metal off than find out it shoots too high for my preferred loads and need to install a taller sight or weld back on some metal. One direction is easy and can be done by just about anyone. The other needs a smith or well equipped metal shop.
I do suggest that if this is your first or just your second time trimming a sight to match the POA to the POI for your load that you sneak up on things. As you say there's some minor but significant variation in frame shape and grip sizing. It takes a few shooting sessions to sneak up on the best hold.
You'll also want to settle on your ammo loads for bullet style and weight and muzzle velocity before you do any final trimming to match the POA to the POI. It's a bit of a commitment since revolvers are affected by this stuff so much.
Ya know I've often thought that if I could work out the loads JUST RIGHT that I could well end up with a slightly hot 240gn load that matches the POI of a milder 200. Where this magic combo ended up I don't know. But I'd sure want a gun that has adjustable sights or to leave the front sight on a fixed model a bit tall until I worked it all out. It would be nice to have some mild 200's at around 750 to 800fps for new shooters or recoil shy folks or days I wanted to just shoot mild stuff. Then to have a stouter 240gn running up around that 950 to 1000 fps range for when I wanted more of a thump. I'm pretty sure it can be done. Just need to put in the time to get there. Then both would work with the same sight height.
I've always wanted to play with my .357 Piettas in that way. I currently shoot CAS events with 130gn LRNFP and 3.8gns of Titegroup. It's a softer load but still perky enough that I feel like I'm shooting a real gun instead of some little poofy thing. It would be fun to load up some .357Mag cases with a 158gn or maybe 180gn bullet and a suitable powder charge for a little more thump that hits at the same POI. Something still well below full power magnums but that would give more of a thump for some range time smiles.
Too may projects.. FAR too little time......