I lube everything. I use a heavy freezer bag and a quick squirt of "Fluid Film"; I put the brass in the bag, and shake and roll it around. Almost impreceptible lube on the brass; I load through a progressive for pistol, and an old Lyman Turret for rifle. The only ones I wipe are 38/357; my GP100 is so tight that a bit of stuck on dirt under the case rim can stop up the cylinder.