I fired slugs outta full choke just to prove you can. I know a guy who firmly believed they would blow the end of the bbl off, I said "watch this".
You get a bit more kick & lousy accuracy with a full choke imo. But they have taken their fair number of deer back in the day when most shotguns you never had an option or choice of choke. I have fired slugs thru my RCT (rifled choke tube) on my Win 1200 and I can honestly say they are accurate out to 100yds and damn good at 50yds, but it leads up...quickly! The way I look at it is after you zero, scrub RCT really good cause you should only need 1 shot,
just my 2 cents