The main differences are the barrel and adjustable trigger. For the most part the rest of the internals are straight from the ISSC mk 22. The other main difference I've seen is how the buttstock plate is retained.
If you check out
http://www.rrdvegas.com/anschutz-msr-rx-22.html .....
You will see that there is a silver metal piece attached to the buttstock. I'm not sure what this does (my theory is it either helps attach the buttstock better or with the assistance of a spring helps provide enough pressure for returning the bolt to battery. In either case, my rifle (which is an earlier poorly made version) lacks this. The ISSC Mk 22 also can have a different mechanism for securing the buttplate/buttstock.
In general, I have a difficult time convincing myself that these came off some production line in Germany (as opposed to a factory in China) as the assembly quality of mine was extremely poor (lots of slop in the stock, various screws loose etc). Perhaps now this is different but for anyone considering this rifle, please do you homework and double check that it is the latest version with the latest upgrades and that it appears correctly put together!
If you are having problems with cycling I suggest you return the rifle to the seller with a number of light struck rounds for proof. Mine had this problem (which is common to early ISSC Mk22, and these rifles). There was a remedy that involved cutting a spring in the bolt to allow for better cycling.
While the seller is checking out your rifle, have the give a once over for the general assembly of your file. Chances are something else might not be set up right and you'll want it fixed before you have further problems.