Any "bushing" thrown loads should be verified on a powder scale, and not taken for granite because of published bushing charts. I haven't found one that's an exact match in any of my scaling trials.
I scale all my bushings at LEAST 7 or 8 times, esp if I'm using a new recipe with a new unscaled powder. Hard to get the exact same throw a few times in a row on a real good day.
As the powder level in your bottle drops, your thrown charges will deviate as the volume in the bottle lessens. (( less pressure by weight is pushing down on the bushing)) ***full bottles compared to 1/4 full always gives you heavier throws.
***That being said, thrown loads will be much more consistent with a powder baffle installed on your loader, the amount of powder being thrown by the bushings, stays more constant and gives you a better averaged, "more accurate throw".
I spent a few evenings, and the odd stormy Saturday running all my different shotgun powders through ALL my bushings...# 16 to # 40..with a few of the A bushings in between numbers. All the while, using my powder baffle. Each one was thrown anywhere from 5 to 8 times. Some gave the same reading 5 times consecutively...others differed by a tenth or two..so I did a few more to get my average more consistent.
Gives me a great bushing# reference point when searching recipes and loads for myself or for friends and colleagues !