You'll notice quite a weight difference between the two rifles, and IIRC the vanguard has a 90 degree bolt throw, and a trapdoor magazine, while the Tikka has a 60 degree throw and a detach magazine.
If it was me, I would make that trade in a second. I'm also very keen on the caliber you're looking at and my next rifle will probably be in that caliber.
I say go for it. I love my Tikka.