Around here the TSX has received good marks from guys who have taken wolves, caribou and moose in 7mm, .30, and .375 caliber. These things just seem to work. The 180 gr TSX load I use in my wife's rifle is 52 grs of H-4350, but her rifle is light and I prefer to keep the recoil down a bit. If you started here you could likely work up a bit.