My buddy bought a .243 last year, and I didn't' have time to reload for it, so I got him some Federal 85gr TSX ammo. Very accurate, and it was amazingly deadly on deer, on both broadside and frontal shots.
It gave me new respect for the 243, which I have always thought of as a bit "marginal" for deer from past experience with my friends using it.. Good bullets make all the difference.