What's best caliber/rifles for coyote/varmint/shooting

The smallest centerfire caliber you already have in your safe, is the most cost effective option. At the end of the day, it is the singer not the song.
 
.233 300yrds +.......22-250 500yrd+ both will suffer wind drift at the further distances. .243 600-800yrds better in the wind than the other 2 calibers. Keep this in mind most hunting action will happen between 3-300 yards. If you are calling where you can see 600-800 yards........ Call em closer! Just sayin. Any of the above would be good choices
 
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