i've got an ambi safety( wilson) on my colt mk 4 series 70, but i'm left handed- that's the reason that there's an awful lot ofambi safeties with the newer guns- as to replacing it with a standard gi , it depends if there's a CLOVER LEAF HOLE ON THE RIGHT SIDE OF THE FRAME- if there is, and you replace that safety with a standard, , you're going to see that hole, - take a look in the gi manual, it's in the frame, just ahead of where the hammer pin and the grip safety goes in- on the LEFT SIDE- if that hole is mirrored, there;s a problem- if all you've got is just the pins coming through to the right side , you should be ok- there's drop in ambi safeties made, so going backwards in the same frame shouldn't be a problem- that being said, when i had my colt fitted, they machined the hole in the right side of the frame and drilled the pin holes one size bigger as it uses a slightly larger pin -in pin combination to fit the ambi side of the safety- in other words the right safety is a mirror of the left but with slightly smaller diameter pin and keyed to coordinate things-