I recall doing a test while at CIL. Customer complained our ammo blew up his gun. The balance of the ammo in his box was loaded with the correct powder (Red Dot) and the powder charge was about right.
I made up some rounds with 50% more powder. (I wanted to go double, but at double I could not get the shells to crimp.) The 50% extra loads shot just fine. They developed higher pressure, higher velocity and more kick, but nothing close to what we would be concerned about so far as damaging a gun.
From time to time I have deliberately blown up guns or shot guns with barrel obstructions. Usually the first attempt fails, and I have to try harder.
The last attempt was a single shot 12 ga. I could not blow it up, and then when I tried to blow the barrel with a variety of obstructions (including a rather large bolt jammed in the muzzle) - nothing happened.
I am not saying "Don't be careful."" But don't lose sleep if you use a different primer.
BTW A good way to blow up a rifle on the first attempt is to substitute a ball pistol powder (296) for a case full of ball rifle powder (Win760). I have seen 4 rifles blow to pieces with that mistake - but I saw one survive. The brass case vaporized.