Island blacktails are my main quarry. To date, I've taken them with the following:
Parker-Hale 1200C, 270 Win, 130gr PSP (1), 140gr TSX factory load (1) (before I started reloading), and 2 with the 110gr TTSX. After using the TSX/TTSX I decided to stick with them. Excellent DRT performance. The 130 PSP kill was not DRT (walked about 30 yards and collapsed) but the bullet came apart and there was meat loss (it was a short range kill). Turned me off using them.
Savage 340, 30-30, with brass trimmed extra short and loaded with the little bitty 110 gr TTSX. 2 with this combo, both DRT.
Husqvarna 640 in 9.3x62, 250gr TTSX. 1 so far. Overkill to be sure, but no meat loss (through the ribs). DRT.