You can make very nice practise ammo on a progressive but these are the bottle necks I found:
taking off the case lube - I size my cases and that lube has to come off. I will not tumble my ammo (makes no sense to me with pointy long bullets). So immediately, the progressives really doesn't work per se. What I do is body size the cases on a single stage press, tumble clean, THEN put into the progressive.
powder dispensing... if you use an extruded powder like H4350, H4831SC and even Varget, there is nothing that will ensure consistency to the 0.1gr... and for precision ammo, that matters. So I use ball powder which can dispense very consistently... however, ball powder can be temp sensitive so you need to adjust for varying seasons. I keep my loads moderate so pressure changes really aren't too drastic.
you can't prep the primer pocket - if that matters to you, there is no way to clean in a progressive.
If you want to trim and deburr on a progressive, you have little control on the final dimensions.
you can't outside neck turn - brass flows and I find outside neck turning really important to maintain neck tension AND stop donuts from forming. Using a Lee collet neck die really helps here.
I use a progressive to make practise ammo. For my match ammo, I use a single stage as I am going to do some brass prep that must be manual processed.
Jerry