I have a 2X-6X Bushnell scope that I pop on and off of my 7.5" Ruger SRH 454 Casull.
It is an amazingly accurate combo...
I sight the scope in with either my 240gr or 300gr XTP-Mag loads and shoot my heavy cast loads with the iron sights.
A feature that I really like about the SRH is that they come with scope rings I do not have to remove or add anything to install the scope I just pop it on and tighten the ring screws and when I want it off I just loosen the screws and pop the scope off...
If I had money to burn I would have a 460 S&W but for the cost of the S&W you can get the Ruger SRH and the scope of your choice...
I'm not finished yet another cool thing is once you get the 454 Casull also buy a LSI Puma M92 rifle chambered in 454 Casull now you have an excellent fun lever action rifle that shoots the same cartridges as you handgun...
For inexpensive plinking I also shoot 45 Colt's in both my SRH's and the Puma rifle...
This rifle also doubles as a defense gun for me and my wife when we are in the bush.