...........The Ruger #1 is a beautiful rifle, but it has some quirks that prevent me from recommending it as a dangerous game rifle. The obvious is that it is a single shooter, but this can be compensated for with proper reloading techniques provided the scope is mounted so as not to cover the feed ramp. I put a custom quarter rib on mine to achieve this. The biggest problem is that the rifle must be carried with a round in the chamber in order to be carried loaded. It bothered me a great deal when after several hours of walking I would unsling to find the safety in the fire position. The spring on the safety seems to push it to the fire position. If the detent is not strong enough, mine wasn't, the normal jostling from walking is enough to disengage the safety. If you attempt to carry the rifle with the action out of battery, the falling block drops open, you loose the round, and you are left with an unloaded rifle.
Another issue can be the lack of caming action that you get from a bolt action. This means that you must be extremely careful when you select the ammo you will take into the field. Each round must be tested to ensure that the action will close without undue resistance. You may even find that you have to machine down the height of a shell holder so you achieve enough shoulder set back on a cartridge that has an abrupt shoulder like the .416 Rigby. Remember, you might be reloading in a hurry! If loads are compressed you had better crimp the bullets in place because when you chamber a round that has a bullet that pushed out, the action will not close. This can even be bad news in bolt actions and the bolt gun has much more mechanical leverage.
The #1 is a beautiful rifle, accurate, handles recoil well, has a good trigger, is nice to carry, but it isn't a dangerous game or protection rifle.