Hard to go wrong with the Partitions - 150, 165, 180. Just stay within a range that has impact velocity above 1,800 fps or so, place it well and get to field dressing and skinning... All will "run out of legs" well before 600 yards, 180's likely before 500 yards - from tables in Nosler 7 manual, trying to guesstimate muzzle velocities for more common 22" barrels in hunting 308 Win rifles. We have taken many dozens of deer at various ranges with 165 HotCor at chrony speed of 2,800 muzzle velocity, and two elk, with same load in 22" barrel Model 70 Winchester. Never shot at moose with it though.