A friend started reloading and it was for a Ruger 30-06. His first load was what we suggested , it was RL22 and a 180 Accubond . Fast , accurate and low pressure. Sadly it was also very boring. He moved on. When you hit perfection with your first try, what do you do ?
I have three 30-06s, a pf M-70 , a M-700 and a P-17 BSA sporter, and have loaded for three more. The BSA gave me quite a surprise, I loaded the standard IMR 4350 and a 180gr load and it went way too fast. well into 300WM territory . I had to back off a fair bit. You can't just assume, even with a 30-06 .
I like IMR 4350, it behaves better than the H 4350. I use VV N560 in place of RL 22. Now I would just load a 165 and call it good. But I have a lot of 180 loaded, so I'll stick with that.