Find a target that works for you. Iron sight the 100 yard challenge target might be difficult to use with irons.
This was shot at 100 yards with Irons. Rather than group size.. we score it like 100-2x
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I know most of my iron sight targets are about a 8inch circle. 50 yard Is smaller, I'll measure them later.
Grab some trail marker tape and make some wind flags. Wind will effect 22LR and gust can go from 9 ring to 7. As for ammo, use what you feel is best. If you are experiencing a huge spread that erratic, try another ammo.
Glare is not your friend when shooting irons.