Yes, 1/10th grain is an absolute nothing with any type of rifle cartridge, with the possible exception of a 22 Hornet, or similar, which are critical at top loadings.
If it is accuracy you are thinking about, bedding of your rifle is far more important than minor changes in powder. If sporting weight rifle barrels have pressure on them at the front of the stock, it absorbs much of the vibrations of the barrel and small changes in powder won't change poi, except at considerable distance.
Anyone who has followed my posts on here, will know that I have preached this for as long as I have been on here. I've told of shooting a five shot group with my 30-06 and 4350 powder, with 4 grains differnce in powder between the hottest load and the lightest, but the five went into a 1.25" group at 100 yards.
I've been adjusting powder charges on my Marlin bolt action 243, to see how the rifle handles pressure. Point of impact stays the same at 100 yards, through a couple of grains of different powder charges. I took the stock off to look at things and was happy to see that Marlin built it with a nice saddle at the front of the stock, to put pressure on the barrel!