The first two deer I ever shot 45 years ago were shot with a 22-250. Didn’t own a deer rifle yet, borrowed a Rem. 788 in 22-250 from my uncle. Was just using factory 55 gr. ammo. First buck I shot was about 125 yards, hit through the lungs, feet in the air like you pulled the rug out under him. The second buck was a little bigger, only about 80-90 yards away, lung shot again, looked like it wasn’t even hit, turned around and trotted into the bush. It only made it into the bush about 30 yards and was stone dead. The blood trail literally looked like you poured a steady stream from a pail to where he dropped and where he dropped there was a huge patch of blood on the ground about 3 feet in diameter. To this day 45 years later, I have shot many deer with 6mm Rem., 6.5x55, and 7mm Rem. Mag. and have never seen a blood trail like that again.