Between me and my hunting partners we killed moose with FTX 325, Barnes 400, Speer 400 and Rem 405. Never had a problem with any of them. All lungs shot and one neck shot. All within 100 yards.
Furthermore, I'm a shooting instructor and early this summer a bullet proof vest company used my services to test their vest with different calibers at a distance of 25 yards.
The calibers were... 9mm, 45acp, 357mag, 44mag, 7.62x39, 223rem. The vest was placed on a 5 gallon jug. None of the bullet went through. The 44mag made a golf ball size impact, the 7.62x39 made a orange size impact.
After we were done testing I asked the owner if I could try a 200grs FTX 460 S&W bullet, he agreed. That bullet (same as the 325 FTX but lighter) went through the front of the vest, through the 5 gallons jug and through the back of the vest. No fragments were found. The vest was placed 4 feet from the dirt back stop. Didn't searched for long but didn't find the bullet in the dirt.
I don't care what some of you are saying, the Hornady 325 grs FTX will kill anything you shoot at. As for dangerous game, I would prefer a hardcast for more penetration but in a hunting scenario the FTX will do whats needed thats for sure.