250 gr .45ACP?
What's your anticipated use for such a heavy bullet for that ctg? Most .45 ACP target loads are 200 gr SWC or 230 gr RN lead bullets.
Both will feed from the magazines of a 1911 and still meet OAL requirements.
I could see a 250 grain load in .45ACP cases for shooting in a wheelgun chambered to take the .45ACP in moon clips, though.