Most guides will not hunt with anyone using a smaller calibre than the .338 win. mag. I have a .300 but dont use a guide, and even then I feel a little nervous. With a 3-9 power scope on it, I can take longer shots (ie. up to 275 yards is my longest comfortable shot), however if I provoke a charge then I have some fast thinking to do. Terrifies me just thinking about it. I have not used a guide and also have not harvested one of these magnificent beasts. Im not sure but I think there is a DVD coming out called "Brown Death", kind of the Black Death take off series.